HER2+ NSCLC: Understanding the Latest Treatment and Advances

Many people have heard of HER2-positive breast cancer. But HER2 is an important biomarker found in many different types of cancer—including non-small cell lung cancer (NSCLC). 

A lot is known about how to treat HER2 in breast cancer, and researchers are leveraging that knowledge to bring treatment options to people living with HER2-positive NSCLC.  

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Countdown to ILCSC24: Bringing the World’s Experts Right to Your Living Room

Read time: 3 minutes.  

One of LUNGevity’s two flagship survivorship events, the International Lung Cancer Survivorship Conference (ILCSC), is being held virtually September 20 – 21, 2024. This is a free, online event that allows people with lung cancer and caregivers from around the world to join from the comfort of their own homes and hear from a star-studded lineup of lung cancer experts discussing the latest advances in research and treatment.  

Repotrectinib Approvals Expand to Include Patients with NTRK+ Solid Tumors

On June 13, 2024, the US Food and Drug Administration (FDA) announced the accelerated approval of repotrectinib (Augtyro™) to treat patients with advanced NTRK-positive solid tumors who have either had their disease recur or who don’t have alternative treatment options. 

This treatment is part of a growing trend of tissue-agnostic drugs—treatments that are prescribed based on the biomarkers found in the tumor rather than the organ where the cancer originated.   

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Safely Bring Yoga, Dietary Supplements, Exercise, and More into Your Lung Cancer Journey

Read time: 2 minutes

Integrative oncology adds holistic approaches—such as acupuncture, nutrition, exercise, and mindfulness—into a treatment plan. Research shows these interventions can have a tremendous impact on people going through lung cancer treatment and their quality of life. Unfortunately, they are also topics riddled with myths and falsehoods. 

LUNGevity spoke to an expert to help sort out the facts from the fiction. 

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FDA Grants Accelerated Approval for HER2+ Cancer Treatment

On April 5, 2024, the US Food and Drug Administration (FDA) announced the accelerated approval of fam-trastuzumab deruxtecan-nxki (Enhertu®) to treat patients with unresectable or metastatic HER2-positive solid tumors.

This treatment is part of a growing trend of tissue-agnostic drugs -- treatments that are prescribed based on the biomarkers found in the tumor rather than the organ where the cancer originated.  

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Lung Cancer Masterclass: Get Smart About Lung Cancer

In the past five years, the lung cancer community has seen an astonishing number of new treatments. As our understanding of lung cancer has deepened, the older treatment approaches have also become more effective and efficient.  

These options are fantastic steps toward improving the overall survival and quality of life for people living with lung cancer, but it can be difficult for patients and caregivers to keep track of the new drug treatments and scientific advancements.  

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Clinical Trial Phases

The four phases of lung cancer clinical trials each serve a different and important purpose. From testing the safety of a new treatment to its effectiveness and long-term outcomes, this short video explains how researchers use clinical trials for new lung cancer treatments.

Phases of a Clinical Trial:

1. Safety of the new treatment 
2. Does the cancer respond to the treatment 
3. Is this new treatment better than the current options 
4. Studies the long-term benefits and side effects

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